by Roger Wedegis
The fusion of two nuclei with lower masses than iron (which, along with nickel, has the largest binding energy per nucleon) generally releases energy, while the fusion of nuclei heavier than iron absorbs energy. The opposite is true for the reverse process, nuclear fission. This means that fusion generally occurs for lighter elements only, and likewise, that fission normally occurs only for heavier elements. There are extreme astrophysical events that can lead to short periods of fusion with heavier nuclei. This is the process that gives rise to nucleosynthesis, the creation of the heavy elements during events such as supernovae.